What is EmbryoGlue and How It Can Affect Your IVF Outcome

A Closer Look at EmbryoGlue

EmbryoGlue is a type of culture medium used in IVF procedures to support embryo implantation. It contains  hyaluronan, a substance naturally found in the body, particularly in the reproductive system. The purpose of  EmbryoGlue is simple: to create an environment that helps the embryo adhere to the uterine lining, improving the  chances of successful implantation. (Source: NIH)  

Hyaluronan helps with cell adhesion, and since it’s present in the body’s natural fluids, it can make the IVF process  feel more like a natural conception. The name "EmbryoGlue" may sound a bit strange, but it reflects its purpose: helping the embryo stick to the uterus, where it can grow and develop. (Source: VitroLife)  

How Does EmbryoGlue Work in IVF?

EmbryoGlue is typically used during the embryo transferstage of IVF. After eggs are fertilized in the lab and embryos  develop for a few days, the doctor transfers the healthiest embryos into the uterus. This is where EmbryoGlue  comes in. By placing the embryos in this special medium it creates an optimal environment that helps the embryos  stick to the uterine lining and begin implantation. 

The idea behind EmbryoGlue is that the better the environment for the embryo, the better its chances of becoming  a healthy pregnancy. It works by mimicking the natural conditions in the uterus, which provides a supportive  atmosphere for the embryo to implant successfully. 

Can EmbryoGlue Improve IVF Success Rates?

While there’s no magic formula in IVF, the growing evidence suggests that EmbryoGlue could significantly increase  the likelihood of implantation. For women who’ve had multiple unsuccessful IVF cycles or those who have struggled  with implantation issues, EmbryoGlue could be a promising solution, potentially changing the game. (Source:  JIVFvv) 

By improving the chances that the embryo will attach to the uterine wall, EmbryoGlue can be particularly helpful  for women who have experienced repeated implantation failure. Some studies suggest that it can increase the odds  of implantation by creating a more favorable environment. While it’s not a guarantee for success, it’s a tool that  could improve your IVF outcomes. 

Is EmbryoGlue Right for You?

If you’re considering an IVF cycle, it’s important to discuss the potential benefits of EmbryoGlue with your fertility  specialist. While it may not be necessary for every patient, it can be a valuable option, especially for those with a  history of implantation issues. Your doctor can assess your unique situation and provide guidance on whether  EmbryoGlue could enhance your chances of success, offering you the support and guidance you need. 

Sources:  

NIH - PMC.ncbi.nlm.nih.gov/articles/PMC4691973/ 

VitroLife - VitroLife.com/ivf-journey/embryo-transfer/ 

JIVFvv - JIVFfww.scholasticahq.com/article/methods-to-improve-frozen-thawed-blastocyst-transfer-outcomes