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Frozen vs. Fresh Embryo Transfers: Which One is Better?

Fresh Embryo Transfer: The Traditional Option

A fresh embryo transfer happens right after your eggs are retrieved. Once your eggs are collected and fertilized,  the embryos are cultured in the lab for a few days, usually 3 to 5, before the best one is selected for transfer into  your uterus. (Source: UR Medicine)  

The main benefit of a fresh transfer is that everything takes place in the same IVF cycle. You don’t have to wait,  which is appealing for many women who are eager to move forward. If your body responds well to the hormone  treatments and your embryos develop as expected, this method can work well. The main challenge is that the  hormonal stimulation involved with egg retrieval can sometimes affect the lining of your uterus, which may reduce  the chances of implantation. 

 

 

Frozen Embryo Transfer: A More Controlled Approach

Frozen embryo transfers, on the other hand, take place in a later cycle after your embryos have been frozen and  stored. Instead of transferring the embryos right after retrieval, your doctor will wait for a future cycle where your  body can better prepare for implantation. This method allows for more flexibility and gives your body time to  recover from the IVF stimulation before the transfer. (Source: NIH)  

One of the big advantages of frozen embryo transfers is that they offer a more controlled environment for embryo implantation. Since the body has time to recover, the uterine lining can be better prepared with the right hormone  levels, improving the chances for a successful pregnancy. This method is especially helpful if you’ve had issues with  ovarian overstimulation or if you’re dealing with conditions like PCOS. 

Frozen embryo transfers also allow for the possibility of multiple tries. If the first transfer isn’t successful, you still  have the option to use your frozen embryos without needing to go through another egg retrieval cycle. 

Which Method is Right for You?

So, which option is better? It really depends on your personal circumstances. Fresh embryo transfers are still widely  used, especially for patients with healthy ovaries who respond well to IVF stimulation. However, the trend is shifting  towards frozen transfers, as they tend to lead to higher pregnancy success rates for many women. 

Frozen embryo transfers are also beneficial if you’re dealing with specific health concerns or if your fertility  specialist wants to make sure your body is in the best shape for a successful transfer. It can also give you the peace  of mind that comes with having extra embryos stored in case the first try doesn’t work out. (Source: HFEA)  

Trusting the Process

Ultimately, the choice between fresh and frozen embryo transfers comes down to your unique situation. Your  fertility specialist will guide you through the decision, taking into account factors like your age, hormone levels,  response to IVF treatment, and overall health. Whether you choose a fresh or frozen transfer, the important thing  is to feel supported and well-informed as you go through this process. 

Sources:  

UR Medicine - URMC.rochester.edu/strong-fertility-center/infertility-treatment-options/ivf/ivf-step-by-step NIH - NIH.ncbi.nlm.nih.gov/articles/PMC6990002/ 

HFEA - HFEA.gov.uk/treatments/fertility-preservation/embryo-freezing/